Subscribe

The Latest Methods in Biohacking and Longevity

In this Ayık Kafa podcast, Dr. Esra Çavuşoğlu, PhD welcomes Dr Joseph Purita, MD.

Dr. Purita is a board-certified orthopedic surgeon with over 20 years of expertise in cellular and anti-aging therapies within the field of regenerative medicine. He completed his undergraduate and medical education at Georgetown University. The orthopedic surgeon turned regenerative-medicine pioneer joins the Ayık Kafa podcast for a sweeping tour of today’s most ambitious longevity tools.

Share this podcast

In this Episode of Ayık Kafa

He explains how therapeutic plasmapheresis (plasma-exchange) works like an “oil change” for the blood, centrifugally discarding a liter-plus of plasma laden with pro-inflammatory cytokines (IL-1, IL-6, TNF-α) and other senescence-associated factors, then replacing the volume with albumin and in the future with placenta-derived exosomes. Purita outlines when to pair exchange with young-blood transfusions, why two back-to-back sessions every six months can serve a healthy biohacker, and how he stacks the therapy with his own EBO2 device an extracorporeal loop that first filters then ozonates, oxygenate, photomodulates (six pulsed light wavelengths) and returns the blood. This procedure helps the system to get rid of viruses, zombie cells, inflammation, microplastics and more. The conversation then pivots to stem-cell strategy (autologous adipose, bone-marrow, and very-small-embryonic-like cells versus off-the-shelf allogeneics), next-gen photo-activation of IV NAD⁺ and methylene blue, red-/near-infrared panels for home use, and Pur-Form’s other modalities—hydrogen-gas inhalation, intermittent hypoxia, whole-body cryo, contrast therapy plus the protein-folding aid “Selbex.” Purita stresses that devices can’t out-run bad habits: he logs daily cardio, 18-hour fasts, targeted supplements, and recommends simple hacks such as blood-flow-restriction cuffs for muscle maintenance post-surgery. Looking ahead, he predicts every medical specialty will adopt regenerative and gene-editing techniques (follistatin, klotho, etc.), accelerated by AI, while clinics like Pur-Form (Boca Raton) and Istanbul’s Only Health act as twin testbeds for what’s coming next.

00:00-04:14 Introduction.
04:14-08:01 What is Plasma Exchange therapy.
08:01-10:29 Albumin & Safety. Why albumin is added after plasma exchange.
10:29-11:41 Comparing plasmapheresis systems: Centrifuge vs. filter units.
11:41-13:19 Who should do it? Ideal users & frequency.
13:19-16:01 EBO2 system details.
16:01-20:23 Description of the toxic waste after EBOO.
20:23-23:41 NRF-2 Gene boost with EBOO.
23:41-25:12 Ozone Hardware tips.
25:12-32:14 Stem-Cell Choices. Fat, marrow, VSELs.
32:14-37:59 What is light therapy: Red and NIR lights.
37:59-42:09 Cryo, contrast, Selbex, more.
42:09-43:23 Hydrogen gas.
43:23-45:19 Lifestyle First. Purita’s daily cardio & fasting.
45:19-47:45 OnlyHealth collab, and future of Longevity.
47:45-51:06 Gene therapies & BFR. Follistatin, klotho, quick muscle fix. Wrap up.

Dr. Joseph Purita, MD:
Website: https://purformhealth.com/about/
Instagram:
https://www.instagram.com/drjoepurita/

*Collaborations & Sponsors:

https://dotshub.com/

Special thanks to T.C. Istanbul Gedik University
https://www.gedik.edu.tr/en/

Disclaimer
The information and statements on our website are not intended to guide individuals towards medical diagnosis and treatment. Please consult with your doctor for medical diagnostic and treatment procedures. The contents are shared for informational purposes only, derived from scientific studies prepared by EMC Medya Yayıncılık Ticaret Ltd. Şti.’s researchers, consultants, and authors/scientists, as well as compilations from publicly available publications. Our texts do not contain health statements related to medical diagnosis or treatment

Subscribe to Longevilab​

Subscribe to our newsletter and stay updated.

Subscribe to Longevilab​

Subscribe to our newsletter and stay updated.

*