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How To Measure and Manage Aging?

In this episode of the Ayık Kafa podcast, Dr. Sandra Kaufmann, MD. In the 1st part of our 2-part podcast series, she discusses her unique approach to longevity and aging, emphasizing the importance of cellular health.

Dr. Kaufmann is an award-winning physician who specialized in pediatric anesthesia at Johns Hopkins, served as Chief of Pediatric Anesthesia at Joe DiMaggio Children’s Hospital, and founded The Kaufmann Anti-Aging Institute, where she developed a comprehensive theory of aging science. She shares her theories on aging, “The 7 Tenets” of cellular decline, and the significance of DNA repair and epigenetics.

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In this Episode of Ayık Kafa

She addresses common health habits and how to mitigate their effects on longevity, while highlighting the role of mitochondria in energy production and overall health. She discusses the complexities of supplement management, emphasizing the importance of understanding bioavailability and dosage. She highlights the critical role of sirtuins in cellular health and longevity, the significance of sleep and circadian rhythms, and the interplay between AMP kinase and mTOR in energy regulation. She delves into DNA repair mechanisms and the impact of inflammation on aging, offering insights into how plants can aid in DNA repair and the benefits of exosomes: She discusses the importance of managing inflammation and its impact on aging, particularly through the use of curcumin and baby aspirin. She emphasizes the significance of cellular health, especially stem cells, and the dangers of senescent cells, which can negatively affect surrounding cells. She outlines protocols for managing senescent cells and expresses her opposition to using external stem cells, advocating instead for the use of exosomes. The conversation concludes with a focus on glycation and its detrimental effects on health, highlighting the need for effective waste management in the body. She discusses various aspects of health, longevity, and the role of supplements and pharmaceuticals in maintaining well-being. She emphasizes the importance of understanding the mechanisms behind aging and how to mitigate damage through lifestyle choices and targeted interventions. The discussion covers topics such as trans-glycosylating agents, the impact of diet soda, navigating toxins in modern life, the use of GLP-1 agonists, and her unique approach to supplement recommendations through the Kaufmann rating system. She shares her personal experiences with medications and supplements, highlighting the importance of a multifactorial approach to health.

00:00-03:13 Introduction to Dr. Sandra Kaufmann
03:13-05:58 The Journey into Longevity
05:58-09:13 Understanding aging and cellular health
09:13-11:49 Dr. Kaufmann’s “The 7 Tenets of Aging”
11:49-15:03 Measuring cellular aging
15:03-17:50 DNA Repair and supplements
17:50-21:03 Epigenetics and its impact
21:03-24:07 Addressing bad habits for longevity
24:07-33:08 Energy production and mitochondrial health
33:08-36:45 Navigating supplement doses and bioavailability
36:45-40:38 Understanding sirtuins and their role in longevity
40:38-49:33 The importance of sleep and circadian rhythms
49:33-52:00 Pathways to longevity: AMP Kinase and mTOR
52:00-56:16 Quality Control: DNA repair and protein maintenance.

Dr. Sandra Kaufmann, MD:
Website: https://kaufmannprotocol.com/bio
Instagram:
https://www.instagram.com/kaufmannlongevity/

*Collaborations & Sponsors:

https://dotshub.com/

Special thanks to T.C. Istanbul Gedik University
https://www.gedik.edu.tr/en/

Disclaimer
The information and statements on our website are not intended to guide individuals towards medical diagnosis and treatment. Please consult with your doctor for medical diagnostic and treatment procedures. The contents are shared for informational purposes only, derived from scientific studies prepared by EMC Medya Yayıncılık Ticaret Ltd. Şti.’s researchers, consultants, and authors/scientists, as well as compilations from publicly available publications. Our texts do not contain health statements related to medical diagnosis or treatment

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