In this episode, I sit down with Dr. Elizabeth Yurth, MD, ABPMR, ABAARM, FAARM, FAARFM, FSSRP. renowned as one of the brightest minds in regenerative and longevity medicine. We discuss the concept of “biohacker syndrome,” exploring why more supplements aren’t always better, as well as diving into cutting-edge therapies like GLP-1 agonists and rapamycin. Dr. Yurth unpacks the myths around cholesterol and NAD, clarifies the hype on biological age tests, and shares how bone health is often overlooked yet essential to long-term vitality. Throughout our conversation, she emphasizes that true longevity relies on balancing the right interventions, not just piling them on.
In this Episode of Ayık Kafa
We also talk about the critical interplay between muscle and bone: why osteoporosis and sarcopenia go hand in hand, and how resistance training remains a cornerstone of healthy aging. From exploring repurposed drugs (like Telmisartan and Cialis) for broader health benefits to understanding why low-dose NAD or antioxidants might be better than high-dose regimens, Dr. Yurth’s insights reflect her deep research background. If you’re looking to sift through the confusion of trendy protocols and focus on science-backed, personalized approaches, this conversation is for you.
00:00-05:29 Introduction
05:29-09:05 “Biohacker Syndrome” Dr. Yurth explains why piling on endless supplements can be counterproductive.
09:05-10:55 From orthopedics to longevity. Her decision to pursue new training in longevity and integrative regenerative medicine.
10:55-12:41 Research and staying up-to-date. How Dr. Yurth keeps current with cutting-edge findings (daily paper reviews, global physician chats). The challenge of separating genuine research from industry-driven agendas.
12:41-15:55 Future of longevity and adaptability. Prospects for living to 120 and beyond.
15:55-18:05 Yamanaka Factors, AI and senolytics. Why total cellular reset may not always be beneficial, and how AI can help.
18:05-20:15 Biological age tests and limitations. Why DNA methylation clocks aren’t yet reliable gold standards. The complexities of measuring true cellular age vs. chronological age.
20:15-25:09 Longevity myths: Telomeres and over-supplementation. Telomeres as only a small part of the puzzle.
25:09-28:36 Risks of excessive antioxidant use and blocking necessary oxidative stress.
28:36-36:06 Importance of bone health and osteoporosis.
36:06-42:17 The problem with constant high-dose NAD. Better strategy is to control CD38 and NNMT enzymes.
42:17-49:09 GLP-1 Agonists for more than weight loss: Protective effects on heart, brain, immune system, and systemic inflammation.
49:09-55:05 Re-examining cholesterol myths. Importance of particle size and ApoB/ApoA ratios rather than just lowering LDL.
55:05-01:02:55 Repurposed drugs for longevity: Rapamycin, Metformin, Telmisartan, Tadalafil and Naltrexone.
01:02:55-01:06:15 Exercise: The ultimate tools. How regular resistance training and daily movement outperform any single drug.
01:06:15-01:08:15 Glutathione IV vs. Precursors.
01:08:15-01:10:22 Conclusion
Dr. Elizabeth Yurth:
Website:
https://boulderlongevity.com/about/dr-elizabeth-yurth/
Instagram: https://www.instagram.com/dryurth?utm_source=ig_web_button_share_sheet&igsh=ZDNlZDc0MzIxNw==
Disclaimer
The information and statements on our website are not intended to guide individuals towards medical diagnosis and treatment. Please consult with your doctor for medical diagnostic and treatment procedures. The contents are shared for informational purposes only, derived from scientific studies prepared by EMC Medya Yayıncılık Ticaret Ltd. Şti.’s researchers, consultants, and authors/scientists, as well as compilations from publicly available publications. Our texts do not contain health statements related to medical diagnosis or treatment